Closed

Preclinical In Vitro Cardiovascular Studies

Ministry of Defence · Value not published · closes 9 Oct 2023

—

Estimated value

Closed

Deadline

5 Sept 2023

Published

Awarded

PHYSIOSTIM SAS£187.9k · to 6 February 2025

Awarded 28 July 2024

This tender has closed.

See what's open in research and development, or get contracts like this in your inbox each morning — free.

Set up free alerts Open research and development tenders

About this contract

The Authority has a requirement for a preclinical in vitro cardiovascular package of work. The Authority wishes to understand the cardiovascular risk and establish QT prolongation potential for a single and multi-drug combination and fulfil the ICH S7B regulatory guidance requirements. These studies are not required to be conducted to GLP but must be in compliance with ICH S7B. A Specialist Review of relevant in house and published cardiovascular safety data is also required to provide a risk assessment and data interpretation to inform decisions on the requirement for any further cardiovascular assessments. The delivery of any recommended cardiovascular assessments may be required as a further Option. A further requirement for integrated risk assessments will be included as an Option. In order to apply, Applicants will need to access www.contracts.mod.uk and create an account and apply by completing the Pre-Qualification Questionnaire.