PHE - Corporate - Prescribed Medicines Review

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About this contract

PHE is conducting a review of the evidence on prescribed drugs that may cause dependence, and the short term discontinuation or longer term withdrawal symptoms, associated with prescribed medicines. Additional information: PHE is seeking an organisation with control of existing datasets that include information on the volume of prescribed medicines in the UK, and able to supply data on the volume (by unit) for each of the drugs included in the review that were: 1. issued within care homes in England; or 2. dispensed on private prescriptions from retail pharmacies. The data would be required by country within the UK (England, Wales, Scotland, Northern Ireland) for the period March 2013 until April 2018 provided in monthly, quarterly and annual illustrations delivered as a single data extract by 30th November 2018. Costs The overall contract value will be a maximum of £12,200 (excluding VAT). A detailed breakdown of costs is required, which will need to demonstrate value for money. How to apply Email details of the raw data you are able to provide and quote with breakdown of costs to Michael.Griffin@phe.gov.uk Drug class (for this analysis) BNF chapter Drugs included Opioids 4.7.2 Buprenorphine Codeine* Dextromoramide Diamorphine Dihydrocodeine** Dipipanone (including with cyclizine) Fentanyl Hydromorphone Meptazinol Methadone Morphine (including with cyclizine) Oxycodone (including with naloxone) Papaveretum Pentazocine Pentazocine Pethidine Tapentadol Tramadol (including with paracetamol) 4.7.1 Codeine with paracetamol = co-codamol* Dihydrocodeine with paracetamol = co-dydramol** Z-drugs 4.1.1 Zaleplon Zopiclone Zolpidem Benzodiazepines 4.1.1 (insomnia) Flurazepam Loprazolam Lormetazepam Nitrazepam Temazepam 4.1.2 (anxiety) Diazepam Chlordiazepoxide Lorazepam Oxazepam Gabapentinoids 4.7.3 Gabapentin 4.8.1 Pregabalin Antidepressants 4.3.1 (Tricyclics) Amitriptyline (including with perphenazine) Amoxapine Clomipramine Dosulepin Doxepin Imipramine Lofepramine Maprotiline Mianserin Nortriptyline Protriptyline Trazodone Trimipramine 4.3.2 (MAOIs) Isocarboxazid Moclobemide Phenelzine Tranylcypromine 4.3.3 (SSRIs) Citalopram Escitalopram Fluoxetine Fluvoxamine Paroxetine Sertraline 4.3.4 (Other antidepressants) Agomelatine Duloxetine Flupentixol Mirtazapine Nefazodone Oxitriptan Reboxetine Tryptophan Venlafaxine Vortioxetine

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