CMOS Camera and Software for CryoTEM

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About this contract

Cutting edge electron cryo-microscopy requires CMOS-based detectors and state-of-the-art imaging software to enable automated collection of high-quality data at high throughput rates. The camera and software are intended for a 120 kV FEI Tecnai Spirit transmission electron microscope (TEM) with cryo-capability. We will record images and tomographic tilt series of single particle protein samples, as well as more complex heterogeneous samples at both room temperature and under cryo conditions. Due to the side-entry cryo holder fitted to our microscope, a fast read-out camera is required in order to account for specimen/ stage drift. The camera must therefore be bottom-mounted and capable of high frame rates, and has to be able to be retro-fitted to the existing TEM. The camera must also be able to acquire single-particle and tomography data sets in an automated manner with fully integrated software. Additional information: How to apply: Applicants will be required to register their interest for the relevant tender documents on the University of Exeter's electronic tendering 'In-Tend' System (http://in-tendhost.co.uk/universityofexeter/asp/home.asp) The procurement exercise is completely managed via this electronic system and only registering on http://in-tendhost.co.uk/universityofexeter/asp/home.asp will ensure that you receive all the relevant information and follow-up document. Registration is free of charge to potential suppliers.

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